Justine (Jennifer Aniston) longs to start a family, but she and loving husband Phil (John C. Reilly) seem unable to conceive. When the frustrated Justine meets a creative, passionate young man named Holden (Jake Gyllenhaal) and begins to fall for him, she gladly escapes into a new world of emotional and sexual awakening ... unaware that the affair could quickly move from liberation to poisonous obsession.