Patrolling the U.S. border with his gun-toting lover, Sartana, after the massacre in Machete (2010), the stone-faced, former Mexican Federale, Machete, receives a call from the president himself of the United States. Thirsting for retribution, Machete embarks on a deadly mission to bring to Texas the megalomaniac Mexican revolutionary, Marcos, who has a nuclear missile pointing at Washington, D.C. Now, Machete and the undercover agent, Miss San Antonio, have to stop a global war, as the shape-shifting assassin, La Camaleón, is hot on their trail. Can Machete's hungry blades avert the impending Armageddon?