Recounting the chaotic events that occurred in Dallas, Texas on November 22, 1963, Parkland Memorial Hospital weaves together the perspectives of a handful of ordinary individuals suddenly thrust into extraordinary circumstances: the young doctors and nurses; Dallas' chief of the Secret Service; an unwitting cameraman who captured what became the most watched and examined film in history; the FBI agents who nearly had the gunman within their grasp; the brother of Lee Harvey Oswald left to deal with his shattered family; and JFK's security team, witnesses to both the president's death, and Vice President Lyndon B. Johnson's rise to power over a nation whose innocence was forever altered.