Tammy, who was recently fired from a Topper Jack's fast-food restaurant, returns home to find her husband enjoying a romantic meal with the neighbor. She quickly packs her necessities, and travels down three houses to her parents' home. Upon denied use of her mom's car to drive to Niagara Falls, she quickly resorts to an "ailing" grandmother, who also lives there--and wants to go along on the road trip. Since Grandma Pearl has the funds, she's in, and they hit the road. Pearl soon proves to be quite the alcoholic despite her diabetes, and Tammy quickly turns into her "minder." From finding love in a bar to robbing a Topper Jack's to bail Pearl out of jail, the quirky adventure will have you finding yourself riding along for the misadventures of Tammy.