Ever since her parents left her as a baby, little Annie (Quvenzhané Wallis) has led a hard-knock life with her calculating foster mother, Miss Hannigan. However, all that changes when hard-nosed billionaire and mayoral candidate Will Stacks (Jamie Foxx) takes her in on the recommendation of his advisers (Rose Byrne, Bobby Cannavale). Stacks believes that he's Annie's guardian angel, but the plucky youngster's confidence and sunny outlook may mean that Annie will save Will instead.