After a flight back home, Sam Hendrix (Efrem Zimbalist Jr.) returns with a doll he innocently acquired along the way. As it turns out, the doll is actually stuffed with heroin, and a group of criminals led by the ruthless Roat (Alan Arkin) has followed Hendrix back to his place to retrieve it. When Hendrix leaves for business, the crooks make their move -- and find his blind wife, Susy (Audrey Hepburn), alone in the apartment. Soon, a life-threatening game begins between Susy and the thugs.