This film follows the sexual escapades of Lily Powers (Barbara Stanwyck), the beautiful daughter of a speakeasy owner. Lily's dreary life in Pennsylvania takes a sudden turn when her father is killed in an accident. Unmoved by her father's death, Lily, along with friend Chico (Theresa Harris), jumps on a freight train and seduces a worker to avoid being arrested. Now in New York City, Lily uses her beauty and sexual prowess to seduce a string of successful men as she works her way to the top.