Boston medical resident Susan Wheeler (Geneviève Bujold) becomes suspicious when her friend (Lois Chiles) is left in an irreversible coma after a routine procedure. Once she uncovers evidence of other patients being left in comas after undergoing procedures in the same operating room, she fears a conspiracy is afoot. When her physician boyfriend, Mark Bellows (Michael Douglas), is skeptical about her findings, Susan must go it alone to uncover the horrible truth.