You thought your life was bad. Try being an incomprehensibly successful writer with a gorgeous wife. Unfortunately for Larry David, co-creator of "Seinfeld", four hundred million dollars and the woman of his dreams (Cheryl Hines) are no match for the constant turmoils that wreak havoc on his daily life. With the help of his manager Jeff (Jeff Garlin) and best friend Richard Lewis (Lewis, playing himself), Larry tries to maintain some semblance of order, but when trouble seems to find you everywhere, that isn't so easy.