In a time of social and political unrest in Haiti, anthropologist Dennis Alan (Bill Pullman) travels to the torn country to study a Voodoo drug used in religious practices to turn victims into living zombies. With the help of a witch doctor (Brent Jennings) and a fellow researcher (Cathy Tyson), Dennis pieces together the deadly mystery. But as Dennis uncovers the secrets behind the mysterious powder, he must evade the Haitian authorities who view his research as a potential threat.